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Extraction et caractérisation du brodifacoum dans un rodenticide commercial

Extraction et caractérisation du brodifacoum dans un rodenticide commercial

Lana Andressa Toth Fernandes

49,68 €
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2024
Materia
Química
ISBN:
9786207194537
49,68 €
IVA incluido
Disponible

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Le laboratoire de l’Institut de criminalistique du Paraná reçoit des morceaux et des miettes de granulés de rodenticides commerciaux provenant d’aliments tels que le café et le thé. Par conséquent, les méthodes de détermination de leurs ingrédients actifs, qui sont principalement des dérivés de la coumarine, sont indispensables dans les enquêtes médico-légales. Cependant, les produits commercialisés ont une faible concentration de ces composés dans leur composition, ce qui les rend difficiles à analyser. L’objectif de cette étude était de développer une méthode d’extraction de la coumarine brodifacoum à partir d’échantillons commerciaux et de la doser par chromatographie liquide à haute performance (HPLC) avec un détecteur à barrettes de diodes (DAD). L’extraction a été réalisée au siège d’Ecoville de l’Université technologique fédérale du Paraná (UTFPR) et le reste de l’analyse au laboratoire de sciences chimiques et biologiques de l’Institut médico-légal (IML) de Curitiba. Une méthodologie a été présentée pour la détermination du brodifacoum dans les appâts commerciaux rodenticides granulés, qui nécessite moins de 10 mg sans avoir recours à des étapes de nettoyage approfondies. La méthode proposée s’est avérée satisfaisante et est actuellement utilisée par l’Institut de criminalistique de Paraná.

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