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Tumores neuroendócrinos digestivos

Tumores neuroendócrinos digestivos

Afef Khanfir / Wala BEN KRIDIS

60,26 €
IVA incluido
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Editorial:
KS OmniScriptum Publishing
Año de edición:
2024
Materia
Tecnología: cuestiones generales
ISBN:
9786207533305
60,26 €
IVA incluido
Disponible

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Sobre IBD

Os tumores neuroendócrinos digestivos (DNET) são raros (menos de 1% dos tumores malignos). Desenvolvem-se à custa de células do sistema endócrino difuso, disseminadas pela parede do tubo digestivo, e representam um grupo heterogéneo de tumores com características funcionais e morfológicas comuns. Na prática, é feita uma distinção entre tumores endócrinos do trato digestivo, tumores endócrinos pancreáticos e tumores endócrinos hepáticos. As circunstâncias em que estes tumores são descobertos variam, dependendo, nomeadamente, do facto de serem ou não funcionais. A síndrome carcinoide é a manifestação clínica caraterística destes tumores. É causada pela libertação de serotonina e de outros péptidos (bradicinina, histamina, substância P, etc.) pelo tumor. Ocorre em apenas 10-20% dos doentes, principalmente quando existem metástases hepáticas. Está tipicamente associada a rubor e diarreia motora. A cardiopatia carcinoide pode estar presente após um longo período de evolução em cerca de um terço dos casos.

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