The process of decrypting innovation and creation, as a lurking nondescript so far, is theorized and operationalized based upon interdisciplinary taskings.First comes the mapping between real world and human brain; innovation is redefined as discovering new interrelationships in the brain using an algorithm, well-defined in 5 steps, of searching unknown relations herein, and the psychological synesthesia governing communications in the brain is dutifully augmented and made to function accordingly. The Dante effect then binds the fresh interactions into a metaphoric tome which is mapped back to the real world to become an up-to-date theory or a new appliance.Since the author has been nurtured both in Chinese spiritual excellence and advanced Western cultures, this book is penned in a provocative style of knowledgeably poetic prose that will appeal to a broad audience.In the era of Artificial Intelligence, it is the human capacity of Thinking Synesthesia acquitted itself with distinction in the profound understanding of various interrelationships that transcends time and will be blessed with eternal youth.