MONOCLONAL ANTIBODIES

This book offers a comprehensive exploration of the groundbreaking use of monoclonal antibody drugs in modern medicine. Beginning with an insightful introduction to monoclonal antibodies, the book delves into the intricate process of their production, from immunization and hybridoma cell preservation to large-scale antibody manufacturing.In its captivating pages, readers will discover the cutting-edge techniques for creating human monoclonal antibodies, including combinatorial and phage display libraries, protein engineering, and gene therapy. The book also illuminates the innovative production of these antibodies using transgenic plants and animals, a frontier in biotechnological research.A pivotal section of this work is dedicated to the diverse applications of monoclonal antibodies in various sectors, including medical diagnosis, cancer treatment, environmental monitoring, and more. It features an extensive list of monoclonal antibody drugs approved by the FDA, offering a detailed examination of each drug, its mechanism of action, and the pivotal clinical trials that led to its approval.The final chapter presents an in-depth analysis of FDA-approved drugs, enriched with detailed diagrams and graphic illustrations. It also highlights the ongoing research and development in the biotech industry, including patent information and the evolving market dynamics of monoclonal antibodies.This book is an invaluable resource for postgraduate students and research scholars in fields like zoology, biochemistry, microbiology, and biotechnology. It also serves as a crucial reference for medical and pharmacy students, offering insights into the latest therapeutic approaches for various diseases. Researchers and professionals in the field of monoclonals will find this book a comprehensive guide, encapsulating three decades of research and advancements in this dynamic area of science.